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PDF) Effect of an Oral Formulation on Skin Lightening: Results from In Vitro Tyrosinase Inhibition to a Double-Blind Randomized Placebo-Controlled Clinical Study in Healthy Asian Participants

* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination

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It is an E3 ubiquitin ligase that facilitates telomere protective protein 1 (TPP1) multisite polyubiquitination and accelerates degradation through binding to TPP1, thereby triggering telomere uncapping, cause cell senescence and tissue fibrosis (Wang L et al., 2020)

or as directed by a healthcare practitioner